An Early and Unequal Decline: Life Course Trajectories of Cognitive Aging in the United States

Citation

Yang, Yang C.; Walsh, Christine E.; Shartle, Kaitlin; Stebbins, Rebecca C.; Aiello, Allison E.; Belsky, Daniel W.; Harris, Kathleen Mullan; Chanti-Ketterl, Marianne; & Plassman, Brenda L. (2023). An Early and Unequal Decline: Life Course Trajectories of Cognitive Aging in the United States. Journal of Aging and Health. vol. 36 (3-4) pp. 230-245 , PMCID: PMC10728348

Abstract

Objectives: Cognitive aging is a lifelong process with implications for Alzheimer?s disease and dementia. This study aims to fill major gaps in research on the natural history of and social disparities in aging-related cognitive decline over the life span.
Methods: We conducted integrative data analysis of four large U.S. population-based longitudinal studies of individuals aged 12 to 105 followed over two decades and modeled age trajectories of cognitive function in multiple domains. Results: We found evidence for the onset of cognitive decline in the 4th decade of life, varying gender differences with age, and persistent disadvantage among non-Hispanic Blacks, Hispanics, and those without college education. We further found improvement in cognitive function across 20th century birth cohorts but widening social inequalities in more recent cohorts. Discussion: These findings advance an understanding of early life origins of dementia risk and invite future research on strategies for promoting cognitive health for all Americans.

URL

https://doi.org/10.1177/08982643231184593

Keyword(s)

cognitive aging cognitive decline

Reference Type

Journal Article

Journal Title

Journal of Aging and Health

Author(s)

Yang, Yang C.
Walsh, Christine E.
Shartle, Kaitlin
Stebbins, Rebecca C.
Aiello, Allison E.
Belsky, Daniel W.
Harris, Kathleen Mullan
Chanti-Ketterl, Marianne
Plassman, Brenda L.

Year Published

2023

Volume Number

36

Issue Number

3-4

Pages

230-245

Edition

June 19, 2023

DOI

10.1177/08982643231184593

PMCID

PMC10728348

Reference ID

10303