Citation
Perreira, K. M.; Hotz, V. J.; Duke, N. N.; Aiello, A. E.; Belsky, D. W.; Brown, T.; Jensen, T.; & Harris, K. M. (2024). The Add Health Parent Study: A Biosocial Resource for the Study of Multigenerational Racial/Ethnic Disparities in Alzheimer's Disease and Alzheimer's Disease-Related Dementias. J Alzheimers Dis. vol. 101 (2)Abstract
BACKGROUND: Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD) have increased in prevalence. OBJECTIVE: This article describes the Add Health Parent Study (AHPS) Phase 2, a study of social, behavioral, and biological factors influencing healthy aging and risk for AD/ADRD, in a national sample of adults aged 58-90. METHODS: Sample members are parents of the National Longitudinal Study of Adolescent to Adult Health (Add Health) cohort, initially interviewed in Add Health in midlife (1994-95). AHPS Phase 1 (2015-17) collected longitudinal data on a random subsample of parents and their spouse/partners, who were mostly Non-Hispanic (NH) White. AHPS Phase 2 will collect the same longitudinal socio-behavioral, and health survey data on all remaining NH Black and Hispanic parents (Black and Hispanic Supplement, BHS). Additionally, Phase 2 will collect cognitive and DNA data from AHPS Phase 1 and BHS sample parents and their current spouse/partners. RESULTS: Funded by the National Institute on Aging, recruitment will occur between June 2025 and May 2026, producing an expected total AHPS sample of 5506 parents and their spouse/partners. CONCLUSIONS: The AHPS will be the first longitudinal cohort study powered to address multigenerational racial/ethnic disparities in AD/ADRD risk and protective factors across race/ethnic groups and socioeconomic strata.URL
https://doi.org/10.3233/jad-240201Keyword(s)
AHPSReference Type
Journal ArticleJournal Title
J Alzheimers DisAuthor(s)
Perreira, K. M.Hotz, V. J.
Duke, N. N.
Aiello, A. E.
Belsky, D. W.
Brown, T.
Jensen, T.
Harris, K. M.