Gene-tobacco policy interaction and adolescent cigarette use


Plurphanswat, Nantaporn & Kaestner, Robert (2012). Gene-tobacco policy interaction and adolescent cigarette use. 2012 Add Health Users Conference. Bethesda, MD.


This study proposes a novel and plausible approach to investigate the importance of gene-environment interactions in determining adolescent cigarette smoking by using the genetic information from the National Longitudinal Study of Adolescent Health. We develop an alternative research design to explore how tobacco control policies may alter genetic influences in determining adolescent cigarette use. In particular, we employ the Blinder-Oaxaca decomposition approach. The basic idea is that the gaps in adolescent cigarette use between adolescents in one environment (e.g. living in high tobacco tax states) and those in another environment (e.g. living in low tobacco tax states) could result from the fact that (1) adolescents in high tobacco-tax states have different genetic markers than those who live in low tobacco-tax states i.e. difference in endowment and/or (2) the effects of these genes differ in high versus low tobacco-tax states. The latter reflects the effects of the gene-environment interactions. The empirical findings suggest the effects of gene-tobacco policy interactions vary by type of policies and by sex. Cigarette use for females seems to be more sensitive to tobacco policy than for males.


Reference Type

Conference proceeding

Book Title

2012 Add Health Users Conference


Plurphanswat, Nantaporn
Kaestner, Robert

Year Published


City of Publication

Bethesda, MD

Reference ID