Citation
Gaydosh, Lauren; Cole, Steve; Shanahan, Michael J.; Levitt, Brandt; & Harris, Kathleen M. (2019). Role of Inflammatory Liability in Modifying the Relationship between Stressful Life Events and Depressive Symptomology. Population Association of America annual meeting. Austin, TX.Abstract
There is a large literature documenting a robust association between major stressful life events and depression and depressive symptoms. While inflammation has been suggested as a potential biological mechanism linking stressful life exposures and depression, this link remains unclear. In this paper, we used data from the National Longitudinal Study of Adolescent to Adult Health (Add Health) to test the role of inflammatory liability in moderating the link between stressful life events and depressive symptomology. We found preliminary evidence that the increase in depressive symptoms associated with greater cumulative stressful life events is steeper for individuals with a gene expression profile of increase inflammatory liability.URL
http://paa2019.populationassociation.org/abstracts/191751Reference Type
Conference proceedingBook Title
Population Association of America annual meetingAuthor(s)
Gaydosh, LaurenCole, Steve
Shanahan, Michael J.
Levitt, Brandt
Harris, Kathleen M.